Endometrial cytokine levels in recurrent pregnancy loss and implantation failure

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Investigation of plasma cytokine levels and endometrial tissue leukocytes in recurrent pregnancy loss

Immigrant and resident leukocytes are the main immune components of endometrial and decidual tissue. Altered immune responses have been suspected to be involved in idiopathic recurrent pregnancy loss (RPL) pathogenesis. We aimed to investigate the plasma cytokine levels and endometrial leukocyte subpopulations of RPL cases. This study was conducted with 60 idiopathic RPL (28 primary and 32 seco...

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Recurrent implantation failure (RIF) has many definitions, but usually authors consider RIF, the failure to achieve a pregnancy fallowing 2-6 IVF cycles in which more than 10 high grade embryos were transferred to the uterus. There are a lot of causes for RIF but two main causes of that are related to embryo and endometrium. Chromosomal abnormalities, zona hardening and problems in culture medi...

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The success of assisted reproduction, although gradually increasing over the years, is still less than satisfactory. Many couples have benefited from this treatment; many have also been left frustrated following multiple failed attempts (Bulent Urman et al. 2005). Repeated implantation failure (RIF), defined as three or more failed IVF attempts or failure of IVF after cumula- Abstracts of the 5...

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Endometrial Granulated Lymphocytes in Women Suffering Spontaneous Early Pregnancy Loss

Spontaneous abortion is the most common complication of pregnancy. Several lines of evidence indicate that immunologic effector cells may play a role in the pathogenesis of idiopathic repetitive abortions. Leukocytes form a substantial proportion of stromal cells in decidua and the endometrial granulated lymphocytes (eGL) is the predominant decidual leukocyte population in the first trimester o...

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Molecular Mechanisms of Recurrent Pregnancy Loss

Introduction: Pregnancy and health is the process in which the egg is fertilized and being able to survive. When pregnancy occurs under some conditions and the fetus is being at risk, it will lead to abortion that occurs involuntarily and spontaneously. Abortions that occur more than two or three times are called recurrent pregnancy loss (RPL). Various etiological factors involved in RPL, inclu...

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ژورنال

عنوان ژورنال: Fertility and Sterility

سال: 2018

ISSN: 0015-0282

DOI: 10.1016/j.fertnstert.2018.07.390